Thursday, September 25, 2008

Health Highlights: Sept. 23, 2008

Title: Health Highlights: Sept. 23, 2008
Category: Health News
Created: 9/24/2008 2:00:00 AM
Last Editorial Review: 9/24/2008

Problems Solved

Flip the pill card over and each unit is plainly visible in its own compartment for quick and fool proof examination. So, while all of the pills are secure, removing them would normally be a problem with such a tight secure seal. However; this is just not the case, because all that someone has to do is simply punch their pill through the seal from behind, using their finger. So, this type of pharmaceutical packaging is a fantastic example of how the industry was able to solve these two problems in one package.

The key catch phrase now in the industry is tamper resistance. In fact, the public has taken so quickly to tamper resistant pharmaceutical packaging, that even street drug dealers are improvising their own types and styles of tamper resistant packaging. The two basic commonalities that all pharmaceutical packaging has in common, is easy access or opening and tamper resistance.

Pharmaceutical Packaging - Everyone's Doing It

Tamper Resistance With Easy Opening

Those cardboard prepackaged pill trays are a prefect example of the combination of these two features. From the top, they are covered with a tight aluminum seal. Once this aluminum seal is broken in any way, it is virtually impossible to hide it. Also, the broad flat aluminum surface makes for easy examination by even the visually impaired, who can feel the aluminum with their finger.

One area of packaging that has undergone the most drastic and dramatic amount of change in recent decades is pharmaceutical packaging. Believe it or not, it wasn't really that long ago that over the counter medication was packaged loosely in boxes and plastic containers. It was the infamous Tylenol poisoning events that woke the public up to the fact that pharmaceutical both over the counter and prescription need to be packaged more securely.



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Family History Key Player in Brain Cancer Risk

Title: Family History Key Player in Brain Cancer Risk
Category: Health News
Created: 9/23/2008 2:00:00 AM
Last Editorial Review: 9/23/2008

Disadvantages

Metronidazole enters an aerobic bacterium where, via the electron transport protein ferrodoxin, it is reduced. The drug then binds to DNA, and DNA breakage occurs. In vitro data suggests metronidazole has antioxidant activity and may prevent and treat rosacea symptoms.

Metronidazole is a nitroimidazole anti-infective medication used mainly in the treatment of infections caused by susceptible organisms, particularly anaerobic bacteria and protozoa. It is considered the gold standard anti-anaerobic agent.

Uses

Yury Bayarski is the contributing author of eMedExpert.com.

It is marketed by Pfizer under the trade name Flagyl in the US, while Sanofi-Aventis markets metronidazole globally under the same tradename, Flagyl. It is also marketed by various generic manufacturers, who sell it at a lower price.

The advantages of metronidazole include:

  • High percentage of sensitive Gram-negative anaerobes
  • Availability as oral and intravenous dosage forms
  • Its rapid bacterial killing properties
  • Good tissue penetration
  • Considerably low chance of inducing C. difficile colitis
  • Price

Mechanism of action

Gold Standard Anti-Anaerobic Medication

  • Intra-abdominal infections, including peritonitis, intra-abdominal abscess, and liver abscess
  • Skin and skin structure infections
  • Bone and joint infections
  • Bacterial septicemia
  • Endocarditis
  • Gynecologic infections (endometritis, endomyometritis, tubo-ovarian abscess, and postsurgical vaginal cuff infection)
  • Lower respiratory tract infections (in combination with another agent with activity against microaerophilic Streptococcus)
  • Adjunct treatment for gastritis and duodenal ulcer associated with Helicobacter pylori
  • Central nervous system infections (meningitis and brain abscess)
  • Bacterial vaginosis
  • Giardiasis
  • Trichomoniasis
  • Amebiasis

Advantages



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